Pesonality D/O (PD)

To be a PD, a pattern of behavior must affect cognition, affectivity, interpersonal functioning & impulse control; it must clinically cause distress and/or functional impairment and have started at adolescence or early adulthood.

Cluster A:Odd&Eccentric (Accusatory, Alone, Awkward)

Paranoid-irrational fears, jealousy; projection is defense mechanism

Schizoid-solitary, indifferent, no psychosis; fantasy is defense

Schizotypal-psychosis (ideas of refernce, magical thinking)

Cluster B:Dramatic (Borderline, Bad, Beautiful*, Babe*; *=in mind only)

Antisocial-impulsive, reckless, non-conformative; act out

Histrionic-shallow&suggestive; repress/dissociate

Narcissistic-self-important; intellectualize, distort

Borderline-mood swings, extreme avoidance of abandonment; splitting

Cluster C:Anxious (Cowardly, Controlling, Clingy)

Avoidant-"inferiority complex" but w/ desire for relation

OCPD-egosyntonic version of OCD

Dependent-exaggerated fear of loniness, low self esteem; regression, somatization

Tx=DBT if destructive, serotonin for impulses

DNA viruses Her HAPPy Pox

HERpes, Hepadna, Adeno, Papova, Parvo, Pox

APP have nucleocap, H,H&Pox have envelopes (herpes env is from nuclear env)

All double stranded except the one that "pleads the 5th" (Parvo/erythema infectiosum); all icosahedral capsid and replicate in nucleus except Pox (in a box w/ own DNAdep-RNApolymerase).

Herpesviruses-latent in-dzs

HSV1-trigem-mainly oral herpes

HSV2-sacral DRG-mainly genital herpes

VZV-thoracolumbar DRG-chicken pox, shingles

EBV-Bcells-infectious mono, Burkitt's lymphoma, nasopharyngeal CA

CMV-leukocytes(macrophages)-cytomegalic inclusion dz, heterophil- mono, NO pharyngitis

HHV6-Tcells-roseola(6th dz) Rash On Stomach & fEver (the fever comes 1st)

HHV8-unknown-8th dz j/k Kaposi sarcoma. 8-kap!

Seps in embryology: Zygote to Blastocyst

Zygote (zygo in greek means "joined" or "union") w/ Zona pellucida; divides @ 1 day

Morula ("Mor" rhymes with "four," here there are 4^2 cells), cavitation starts here

Trophoblast - cells begin secreting fluid into the morula ("Troph" means nourishment [atrophy=no nourishment]); not totipotent as trophoblast

Blastocoel=fluid cavity in trophoblast, Zona pellucida begins being "blast"ed away

Blastocyst=Trophoblast+Blastocoel+inner cell mass; pre-implantation state; ~5 days after fertilization; 70-100 cells; IVF possible from day 2 to now

According to wikipedia, toxin exposure up to 2-3 weeks results in miscarriage; after that toxin exposure causes malformations

Neuro viruses

Herpes Simplex-dorsal root/sensory neuron->localized blisters/cold sores
Herpes Zoster-dorsal root/sensory neuron->shingles (Think "Zoster-brand shingles")
Rabies-retrograde axonal transport (sensory & autonomic nerves affected--hence hypersalivation)

Polio-anterior (ventral) root/motor neuron->paralysis
Other Enteroviruses-hematogenous, cross BBB->meningitis, encephalitis (esp Coxsackie)
And Arboviruses cause encephalitis

PAIN fibers cross in the sPAINal cord; vibration, touch, pressure cross in medulla

Roseola, Rubeola, Rubella, etc

ROSEola (6th dz) from HHV-6 = Rash On Stomach ~3 days after high fEver

Rubeola (Measles) = Constable (Koplik) Measle has Ruby-red eyes w/ rash head (1st) to toe (last)

Rubella = "Little Red" mimicks RUbeola but not as high fever, not as prominent rash, and no Koplik spots despite being called "German Measles" (Koplik sounds German, right?)

Variola = small pox

Varicella = chicken pox, rash mainly on head and trunk

Molluscum contagiosum = "pox pimple"

Exanthem subitum = 6th dz aka roseola

Erythema infectiosum = 5th dz aka slapped cheek dz (don't spread infectiosum by slapping others high-five)

Erythema nodosum = rash on shins, ulcerative colitis (nod and look at your shin)

Erythema multiform = allergic reaction to infection (HSV) or medication (pencillin, sulfas, barbs)

Note: Oatmeal has been scientifically found to reduce itching.

Brachial plexus I/O & injury

C5,6,7->UPPER trunk->MUSCULOcutaneous (think upper trunk helps you show-UP your MUSCLes [supinate forearm and elbow flex--how else do you show your big guns?])

C7->middle trunk->Radial, Axillary, and Median (remember Radial injury=wRist dRop [posterior cord])

C8,T1->lower trunk->Ulnar (UL=LOW backwards and my U's look like C's for Claw hand)

Radial N injury doesn't sound Profundly Humerous (profunda brachial A near Radial N)

Nerve Injury Mnemonics! Oh yeah!

Nerve damaged-Resulting loss/problem

Radial Nerve-wRist dRop & doRsal sensation

Ulnar-Claw hand w/ pinky and palm sensation (my U's look like C's sometimes, so this works in my mind)

Median-Me Done with this post (thumbs up![no thumb opposition])