Saturday, November 21, 2009

DNA viruses Her HAPPy Pox

HERpes, Hepadna, Adeno, Papova, Parvo, Pox
APP have nucleocap, H,H&Pox have envelopes (herpes env is from nuclear env)
All double stranded except the one that "pleads the 5th" (Parvo/erythema infectiosum); all icosahedral capsid and replicate in nucleus except Pox (in a box w/ own DNAdep-RNApolymerase).
Herpesviruses-latent in-dzs
HSV1-trigem-mainly oral herpes
HSV2-sacral DRG-mainly genital herpes
VZV-thoracolumbar DRG-chicken pox, shingles
EBV-Bcells-infectious mono, Burkitt's lymphoma, nasopharyngeal CA
CMV-leukocytes(macrophages)-cytomegalic inclusion dz, heterophil- mono, NO pharyngitis
HHV6-Tcells-roseola(6th dz) Rash On Stomach & fEver (the fever comes 1st)
HHV8-unknown-8th dz j/k Kaposi sarcoma. 8-kap!

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